Sialoglyco2018 opens with an evening reception on Thursday 10th May. This mixer coincides with the poster session of the Glycomics symposium, and on the following day, our first scientific session is scheduled as a joint session with the Glycomics symposium. In total, Sialoglyco2018 hosts three days of scientific sessions, one afternoon of which is free.  The conference will finish on Sunday, May 13th with a dinner banquet.  Breakfast will be provided to attendees prior to their departure on Monday, 14th May.

THURSDAY 10 MAY
3:30–5:00pm Registration
5:00–8:00pm Opening Mixer – Joint with Glycomics Poster Session
 
FRIDAY 11 MAY
7:00–8:30am BREAKFAST
Joint Glycomics and Sialoglyco2018 Session
Chair: José Méndez Campos, University of Toronto
8:30am KEYNOTE 1
Herbert Hildebrandt, Hannover Medical School
Novel insights into polysialic acid functions in brain development and disease
9:10am ORAL PRESENTATION
Corwin Nycholat, Scripps Research Institute
Synthetic glycan analog libraries for the development of high affinity ligands of glycan binding proteins
9:30am ORAL PRESENTATION
June Ereño-Orbea, Hospital for Sick Children
Molecular basis of CD22 function and therapeutic targeting
9:50am ORAL PRESENTATION
Natalie Bamford, University of Toronto
Structural insights into biofilm polysaccharide deacetylation in the fungi Aspergillus fumigatus
10:10am KEYNOTE 2
Gesa Volkers, University of British Columbia
Structure-based analysis of polysialyltransferases
10:50am MORNING BREAK
11:20am ORAL PRESENTATION
John Klassen, University of Alberta
Competitive universal proxy receptor assay (CUPRA) for quantitative high-throughput glycan library screening
11:40am ORAL PRESENTATION
Carmanah Hunter, University of Alberta
Chemical tools for the study of natural and labile sialic acids
12:00pm ORAL PRESENTATION
Landon Edgar, Scripps Research Institute
Programmable T cell responses through Siglec-1* macrophages
12:20pm KEYNOTE 3
Robert Yu, Augusta University
Glycobiology of neural stem cells– Role of glycolipids in cell fate determination
1:00pm LUNCH
 
Sialic Acids in Disease
Chair: Warren Wakarchuk, Ryerson University
2:00pm Welcome Address
Andrew Bennet, Conference Chair
2:10pm PLENARY LECTURE 1
Ajit Varki, University of California, San Diego
Sialic Acids: A Nexus in the Pathobiology of Human Infectious Diseases
2:50pm ORAL PRESENTATION
Philippe Delannoy, University of Lille
TNF differentially regulates ganglioside biosynthesis and expression in breast cancer cell lines.
3:10pm POSTER LIGHTNING TALKS
3:30pm AFTERNOON BREAK
3:50pm PLENARY LECTURE 2
James Paulson, Scripps Research Institute
Siglec suppression of immune cell responses and home prices: Location, location, location
4:30pm ORAL PRESENTATION
Marjan Huizing, National Institutes of Health
Concerted Action for Therapies of Free Sialic Acid-Related Disorders
4:50pm ORAL PRESENTATION
Ian Schoenhofen, National Research Council of Canada
Neisseria gonorrhoeae therapeutics based on the CMP-sialic acid scaffold: Efficacy, stability and safety of lead candidates
5:10pm KEYNOTE 4
Jamey Marth, University of California, Santa Barbara
Sialic Acids and Neuraminidase Activity in Inflammatory Diseases
5:40pm END OF SESSION
 
SATURDAY 12 MAY
7:00–8:30am BREAKFAST
SialoglycoChemistry and Chemical Biology Tools
Chair: Mark von Itzstein, Griffith University
8:30am KEYNOTE 5
Cristina De Meo, Southern Illinois University
Effect of O-Protecting Groups in Sialylation Reactions
9:00am ORAL PRESENTATION
Dennis Whitfield, Sussex Research Laboratories
Thermal route to bacterial nonulosonate-enes
9:20am INVITED PRESENTATION
Chris Cairo, University of Alberta
Inhibitors of the human neuraminidase enzymes as probes of biological function
9:40am YOUNG INVESTIGATOR
Cinzia Colombo, Università degli Studi di Milano
Design and synthesis of candidate inhibitors of influenza A neuraminidase based on constrained bicyclic molecules
10:00am KEYNOTE 6
Yasuhiro Kajihara, Osaka University
Chemical Synthesis of Homogeneous Sialylglycoproteins
10:30am MORNING BREAK
11:00am KEYNOTE 7
Thomas Boltje, Radboud University
Chemical Tools to Modulate Sialic Acid Expression and Recognition
11:30am INVITED PRESENTATION
Akihiro Imamura, Gifu University
Chemical synthesis of structurally complex gangliosides via unique synthetic approaches
11:50am ORAL PRESENTATION
Shang-Cheng Hung, Academia Sinica
One-Pot Synthesis and Binding Interaction of Sialylated Glycans with Hemagglutinins
12:10pm INVITED PRESENTATION
Jennifer Kohler, University of Texas Southwestern Medical Center
Discovery of host cell receptors for bacterial toxins using photocrosslinking sialic acid
12:30pm KEYNOTE 8
Hiromune Ando, Gifu University
Chemistry and Chemical Biology of Sialic acid
1:00pm LUNCH
AFTERNOON FREE
 5:00-6:30pm POSTER SESSION
SUNDAY 13 MAY
7:00–8:30am BREAKFAST
SialoglycoBiology
Chair: Rita Gerardy-Schahn, Hannover Medical School
8:30am ORAL PRESENTATION
Kay-Hooi Khoo, Academia Sinica
Delineating terminal di- and oligosialylation carried on glycoproteins from mouse brain deficient in ST8Sia3 by mass spectrometry-based glycomics
8:50am ORAL PRESENTATION
Di Wu, Nagoya University
Different fates of three medaka mutants in the CMP-Sia synthetase (CSS) gene, I230N, L303Q, and null mutants
9:10am ORAL PRESENTATION
Takashi Angata, Academia Sinica
Soluble Siglec-14 is generated by alternative splicing and suppresses myeloid inflammatory responses
9:30am INVITED PRESENTATION
Chihiro Sato, Nagoya University
G x E views of polysialic acid expression
9:50am ORAL PRESENTATION
Barbara Bensing, University of California, San Francisco
Streptococcal Siglec-like Adhesins Recognize Different Subsets of Human Plasma Glycoproteins: Implications for Infective Endocarditis
10:10am Robert Woods, University of Georgia
Engineering High-Specificity Affinity Reagents for the Detection of Glycan Sialylation
10:30am BREAK
11:00am ORAL PRESENTATION
Nathalie Juge, Quadram Institute Bioscience
Sialic acid metabolism by the gut symbiont Ruminoccocus gnavus
11:20am INVITED PRESENTATION
Alexey Pshezhetsky, University of Montreal
Mammalian Neuraminidases in regulation of signaling and metabolism
11:40pm ORAL PRESENTATION
Yuuki Kurebayashi, University of Shizuoka
Low-pH stability of neuraminidase isolated from H7N9 influenza virus
12:00pm ORAL PRESENTATION
Warren Wakarchuk, Ryerson University
Directed evolution of bacterial polysialyltransferase for in vitro synthesis of polySia
12:20pm ORAL PRESENTATION
Nora Heisterkamp, Beckman Research Institute, City of Hope
Sialic acids in precursor B acute lymphoblastic leukemia
12:40pm ORAL PRESENTATION
Ken Kitajima, Nagoya University
Comparative studies of the insect and vertebrate sialate 9-phosphate synthase (SPS)
1:00pm LUNCH
SialoglycoScience
Chair: Nathalie Juge, Quadram Institute Bioscience
2:00pm KEYNOTE 9
Yann Guerardel, University of Lille
Sialomics of zebrafish – Diversity and metabolism of sialic acids in Danio rerio
2:30pm ORAL PRESENTATION
Malena Albers, Hannover Medical School
Impact of the acetyl-CoA transporter AT-1/SLC33A1 on sialic acid O-acetylation
2:50pm YOUNG INVESTIGATOR
Wesley Zandberg, University of British Columbia – Okanagan
The development and use of analytical techniques to quantify the sialic acids borne by gut mucins and milk glycoconjugates
3:10pm YOUNG INVESTIGATOR
Matthew Macauley, University of Alberta
Changes in Sialic Acid during B-cell Differentiation Controls the Germinal Center through CD22
3:30pm BREAK
3:50pm YOUNG INVESTIGATOR
Anja Münster-Kühnel, Hannover Medical School
Interfering with sialoglycan biosynthesis in mice: From embryonic lethality to kidney failure
4:10pm YOUNG INVESTIGATOR
Wenjie Peng, Shanghai Jiaotong University
Resolving the Interactions between Human Hemagglutinin and Sialoside Ligands by NMR Study
4:30pm YOUNG INVESTIGATOR
Lisa Willis, University of Toronto
Polysialic acid and cancer
4:50pm YOUNG INVESTIGATOR
Arun Everest-Dass, Griffith University
Dissecting the interplay between glycosphingolipids and protein glycosylation to understand ovarian cancer metastasis
5:10pm INVITED PRESENTATION
Amanda Lewis, Washington University
Sialidase activity drives glycan foraging and symbiosis between Fusobacterium nucleatum and the vaginal microbiota
5:30pm CLOSING REMARKS
7:00–9:30pm CONFERENCE BANQUET
MONDAY 14 MAY
7:00–8:30am BREAKFAST
8:30am Departure